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Abstract : This research presents a new spectrophotometric method for the determination of furosemide by oxidation and coupling reaction. The method used potassium chromate as an oxidizing agent for phenothiazines, which is then combined with a furosemide acidic medium to form a stable product with orange color. The experiments showed highest absorption at 450 nm, with molar absorption coefficient of 2282.1405 l.mol-1.cm-1 and Beer limits range (2-150) µg/ml.

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