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Abstract : The prevalence of acne vulgaris is on the rise in Saudi Arabia. However, limited research work has been reported with no studies found on medical students. The current study aimed to estimate the prevalence of acne vulgaris among medical students at Tabuk University and to investigate its association with lifestyle, including stress, sleep, and dietary habits. This cross-sectional survey study was carried out during April to July 2021. A structured questionnaire was designed and presented to 429 students with a response rate of 70.2%. This study included 301 medical students of Tabuk University. The prevalence of acne vulgaris was 71.1%, where 42.2% of students reported current acne and 28.9% reported past acne. Less than half (45.3%) got medical consultation for treatment. Mild, moderate, and severe were reported in 41.1%, 51.9%, and 7% respectively. Hormonal changes, sleep deprivation, or combinations of factors are the most aggravating factors (74.8%). While food was the culprit in 32.9%. Female gender, oily skin type, face cleanser (only once/month), and moderate to major stress were significantly associated with the development of acne (p<0.001) with 78.4% accuracy, 91.1% sensitivity, and 47.1% specificity. Oily skin type and major stress showed the highest odds ratios (7.46 and 6.75, respectively). Acne vulgaris affects large percentage (71.1%) of medical students at Tabuk University. Risk factors that increased the likelihood or aggravated acne included stress and lack of face washing by a cleanser, besides being a female with an oily skin type.

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