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Abstract : This study evaluates the association between acetyl choline esterase and some antioxidant markers in the plasma of β-thalassemia patients divided to (85 with β-thalassemia major and 15 with β-thalassemia intermediate) and 50 healthy subjects as control. Antioxidant markers including: total protein, albumin, globulin, albumin/globulin ratio, free amino, free amino / total protein, thiol, thiol / total protein, carbonyl and carbonyl / total protein. The results showed that there was a significant increase in the activity and specific activity of acetyl cholinesterase, total protein, albumin, globulin, thiol, free amino and carbonyl in β-thalassemia patients compared with control group. The results above indicated that these parameters may be good biochemical markers for the evaluation of disease.

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