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Abstract : Cancer remains one of the leading causes of mortality among non-communicable diseases worldwide, underscoring the need for extensive searches for effective treatments and therapeutic agents. Resveratrol, a naturally occurring polyphenol, has been the subject of interest in many cancer studies for its anti-cancer potential and is continuously being studied to this date. This scoping review aimed to provide an updated synthesis of the cytotoxic and cytostatic activity of resveratrol, focusing on in vitro and in vivo studies published from 2019 to 2024. Using PRISMA-ScR guidelines, this review has identified the molecular mechanisms of resveratrol, including apoptosis induction, modulation of autophagy, and inhibition of proliferative pathways. The key findings of this study contribute to the supporting evidence of resveratrol’s anticancer potential, emphasizing the further need for clinical trials to validate its therapeutic effects.

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