The aim of this study was to evaluated the effect of distilled water, tea, coffee and cola on color change of poly ether ketone CAD-CAM, 3D printing and heat cure acrylic resin denture base at 6 days. Materials used are PEEK CAD-CAM, 3D printing denture and heat cure acrylic resin. Samples design was disk shape with uniform dimension 10 mm (diameter) × 2 mm (thickness). Total number of samples are n= (75) samples, control samples not immersed in beverage media n= 15, experimental samples immersed in beverage media (distilled water, tea, coffee and cola) n=60 for evaluating the color change at 6days, using colorimeter tester. Then all collecting data were statically analyzed by spss version 25, by means of descriptive statistics, analysis of variance (ANOVA) and duncan multiple range tests at p ≤ 0.05. The results showed significantly increasing in color change at p ≤ 0.05. All beverage media negatively affected all of experimental materials. The most color change was in tea then in coffee then in cola while the least color changes was in distilled water.