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Abstract : This study was conducted to investigate the adverse effect of Energy Drinks (Red Bull and C4) taken by athletes in some blood and biochemical parameters which include lipids profile (HDL and LDL), Liver Function (AST, ALT, ALP, Bilirubin and Albumin), B. urea, Creatinine for kidney functions tests andHbA1C, ECG. The results indicated significant difference in biochemical parameters of athletes used EDs; there was a significant (P < 0.05) in the levels of Aspartate amino Transferase (AST), Alanine amino Transferase (ALT), Alkaline Phosphatase (ALP), Bilirubin and Albumin in athletes consumed deferent type of energy drinks (Red bull and C4) in different period of time when compared with control group. Also it was showed a significant (P < 0.05) in the levels of serum creatinine and blood urea compared with control group. Finally, the results also showed a significant (P < 0.05) in the mean of Low Density Lipoprotein (LDL) in experimental group when compared with control group. On other hand the results also showed a significant decrease (P < 0.05) in the mean of High Density Lipoprotein (HDL) in experimental group when compared with control group.

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