The mental foramen (mf) is a strategically significant landmark; to avoid mental nerve damage, its location, morphology, and anatomical variances must all be evaluated before operation. The mental foramen is a complicated region with several anatomical peculiarities. The nerve can be damaged in various ways, including endodontic treatments and overfilling, tooth extractions, and surgical procedures such as implantology; it can result in temporary sensitivity symptoms comparable to labiomental paresthesia. CBCT enables the collection of detailed information on the mf anatomy, its surroundings, and anatomical changes that may occur when clinical factors such as sex, side, or dental status change. When two-dimensional and three-dimensional images were compared, several differences were discovered. The average distances observed with cbct between the mf and the midline and between the mental foramina were larger than those assessed with pan. CBCT was used to determine the locations of the mental foramen and their relationship to the mandibular posterior teeth and the thicknesses of the cortical plates of lower premolars and molars teeth.