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Abstract : <p>This Study was conducted in Diyala Governorate/ Iraq. For a patient with type-1 Diabetes, this Study aimed to evaluate some of the cellular kinetics that causes inflammation in the pathogenesis of type1 Diabetes by measuring the level of TNF-a, as they were determined using ELISA technology (sandwich Enzyme _Linked Immunosorbent Assay). After that, H.pylori bacteria were added to this research. The aim was to determine the relationship between Helicobacter pylori and its association with type1 Diabetes by measuring this bacteria&#39;s level of globulin (IgG, IgM) and knowing the immunopathology. Sixty samples were collected from type 1 diabetes patients after diagnosis. According to the criteria approved by the world Health Organization for diagnosis of type 1 diabetes, the number of males was (35), and the number of females was (25). Forty blood samples were taken from apparently healthy people, which were adopted as a control group if the number of males reached (20), and the number of females was (20). The level of cellular kinetic that was measured in this Study was determined; the results showed an increase in the level of Tumor necrosis factor-alpha (TNF-a) among the group of patients (234.9406&plusmn;121.753361) pg\ml compared to the healthy group (62.4782&plusmn;18.21447) pg\ml.</p>

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