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Abstract : Intra-uterine insemination (IUI) with washed sperms has been the most widely used methods alternative in ART. Thus many studies have been done for more success of IUI. To assess the effect of cervical mucus aspiration prior to intrauterine insemination (IUI) on pregnancy rate. This was a prospective randomized study was conducted between November 2017 and May 2018 at Fertility Centre of Al-Najaf city/ Iraq. A total of 112 subfertile women included after initial assessment and investigation. They randomly divided into two groups. Treated group with cervical mucus aspiration before IUI (n=56) and non-cervical mucus aspiration as control group (n=56). The main outcome measure was pregnancy rate. Two groups were matched regarding age, type, cause, or duration of subfertility, and number of follicles. Pregnancy rate in treated group was 17.9% which is higher than 10.7% in control. This difference was not statistically significant. Pregnancy rates were insignificantly different between groups with or without cervical mucus aspiration; further studies are needed for further assessment.

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