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Abstract : PCOS is one of the most common metabolic endocrine disorders affecting women of reproductive age. Zinc, is important trace element in the body. It is required for "DNA, RNA, and protein synthesis, cell-mediated immunity& reproduction". "Lack of antioxidants and oxidative stress" may negatively influence oocyte quality and conception rate. Is to measure the zinc contents in the follicular fluid of infertile PCOS women having ICSI in order to assess oocyte number and quality. A cross-sectional study was conducted on 80 subfertile polycystic ovarian women between the ages of 20 and 40 who were referred to the reproductive clinic at ALSadder teaching hospital and had Intra Cytoplasmic Sperm Injection (ICSI). Determine the zinc concentration in follicular fluid. In addition, oocyte maturation and embryo quality were evaluated using inverted optical microscopy. Follicular fluid zinc does not have a significant correlation with metaphase I (MI)" and "germinal vesicle", but it has a substantial positive correlation with the number of total oocytes, MII oocytes, total embryos, and Grade I embryos. GI embryo numbers and the amount of FF zinc in women's ovaries who were candidates for ICSI treatment and who had a history of PCOS were shown to be highly correlated. This was also true for the number of oocytes and the quality of those oocytes.

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