Abstract : Coronavirus illness (COVID 19) developed in China and spread over the globe. The reproductive system is a high-risk target for SARS-COV 2 infection and countrywide immunisation with Pfizer-BioN tech and other vaccines. No proven proof of illness and vaccine's influence on future fertility. To assess the possible effect of COVID 19 infection and vaccine on ovarian reserve in reproductive age women in Iraq. A case-control research conducted at Kamal Al-Sameraie hospital for infertility and IVF, Al- Nada specialised private centre for IVF, Baghdad Iraq, and Al Najaf infertility and IVF facility, Al Najaf Iraq, from June 2021 to June 2022. 150 infertile women of varying ages are randomly separated into infected, vaccinated, and non-infected non-vaccinated groups. More over two-thirds of infected individuals had mild COVID-19 infections, but only 36% of vaccinated patients had mild reactions. AFC, serum FSH, and AMH levels in the vaccinated group were (10.664.46, 6.963.23, 1.821.03) whereas in the control group they were (126.64, 6.262.23, 2.512.44) with no significant difference (P>0.05). There was also no significant change in ORT (AFC, FSH, AMH) between infected and control groups. Serum AMH levels in the infected group were (2.051.46) before infection and (1.871.42) after infection (P=0.5). There was no significant change in the vaccinated group before and after immunisation (P=0.4). No significant changes were identified in COVID-19 infected group ovarian reserve markers (P>0.05). Covid 19 infection and vaccine did not appear to affect ovarian reserve, function and future fertility in reproductive age women.