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Bulletin of National Institute of Health Sciences

Journal ID : BNIHS-25-05-2022-10340
Title : Prediction of the optimum radiotherapy plan of Parotid gland cancer by the Homogeneity Index
Abstract :

Homogeneity Index (HI) is one of the objective tools that evaluate the homogeneous distribution of dose in the target volume (TV). Therefore, it is used to assess the quality of different treatment plans. This research aimed to study the dependence the HI as comparative tool for evaluating the optimization of different 3DCRT plans for parotid glands’ tumors. This research included (11) patients with parotid gland tumors. Patients have been subjected to a CT simulation and the scans were fed to the radiotherapy planning system. The TV of each patient was contoured to perform five 3DCRT plans for each case. The value of HI was calculated for each plan, and the HI values were statistically analyzed. The third applied plan (Ipsilateral mixed electron - photon beams) provided the highest HI value as compared to the other four 3DCRT techniques. The 3DCRT planning techniques of the increased photon beams provide the maximum dose distribution homogeneity to the planning target volume of the parotid gland.

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Journal ID : BNIHS-21-05-2022-10339
Title : Synthesis , Characterization And Evaluation Antibacterial Activity For Mixed-Ligand Complexes Of Saccharine and Acetylacetonato
Abstract :

Saccharine and its complexes have critical importance with biological and pharmacological properties. The main objective of this study was to synthesize the mixed ligand complexes from the complexes [M (Sac)2 (H2O)2] [M: Zn(II), Cd(II), Hg(II), Fe(III), Ni(II) and Cu (II) with a second ligand (acac), The structures of the complexes were characterized by elemental analysis, FT-IR, magnetic susceptibility, UV-VIS., molar conductivity, According to the experimental results, it was determined that saccharin complexes coordinated with four molecules of H2O and two molecules of saccharin, second step include established four molecules of H2O to the second ligand (acac) it was coordinated to the metal ions via oxygen atom of carbonyl group in saccharin and acetylacetonato, In antibacterial activity, study was determined to occur significant inhibition zones, It is obtained that the complexes exhibited the highest inhibition zone in compared with the free two ligands.

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Journal ID : BNIHS-20-05-2022-10337
Title : Evaluation of the therapeutic efficacy of aloe vera juice on weight, liver and Renal function in laboratory rats induced with diabetes
Abstract :

The active ingredients of aloe vera juice were flavonoids and polyphenols 5.1 mg/g and 8.6 mg/g, respectively. The experimental animals were distributed, ranging in age from 8-9 weeks and weighing 230-238 grams. These animals were distributed into three groups, in each group five animals, Where 15 animals were used in this study, in which diabetes was induced by injecting them with alloxan at a dose of 165 mg/kg of body weight. After that, daily doses of aloe vera juice were given in two doses per day, at the rate of 1 ml of aloe vera juice, orally for a period of 28 days. The weights of the animals were also measured, as their weights ranged between 230-238 g before dosing, the significant values of weight gain in the treated groups were 43.0, 35.0 and 33.3 g, respectively, while the value of the affected group was -8.3. Also, the blood sugar was estimated and its values were 435.67, 452, and 430.67 Mg/dl, respectively, for groups treated with aloe vera juice after infection, then decreased to 108.66, 128.33 and 122.33 Mg/dl, respectively, at the end of the experiment. This study aimed to know the effect of aloe vera juice on rats induced with diabetes, and to know the ability or potential of aloe vera juice to reduce some complications associated with diabetes.

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Journal ID : BNIHS-19-05-2022-10336
Title : Remediation of Eosin Stain from Wastewater using Different Techniques: An Article Review
Abstract :

The production and accumulation of waste water of its various types constitutes one of the serious environmental problems, due to the fact that it contains toxic and carcinogenic substances that can lead to the deterioration of any ecosystem, and thus affect human health directly or indirectly through its transfer to it through the food chain. The components of waste water that are released to environmental systems include various types of pollutants such as heavy metals, organic materials, residues of fertilizers, pesticides, industrial detergents, petroleum and its derivatives and the associated oil residues, fats of different density, acids, alkalis, and biological pollutants such as bacteria, fungi, algae, parasites, viruses and other microorganisms, among others. The most common types of these pollutants are dyes. The current paper deals with a review of methods for treating polluted water with one of the most important and most widely used types of dyes in the field of medicine, veterinary medicine and life sciences, which is the eosin dye that is used in many industries in addition to its use in the medical and biological fields. Where there are many methods and techniques that have studied the removal of this dye from contaminated aqueous solutions with different design conditions. The purpose of this review article ends with two points. The first is to shed light on this toxic dye that is posed in not small quantities by industrial, laboratory, medical and biological activities alike. As for the second, it is the inclusion of the importance of treating the water presented to the various waterways and polluted by this character through a review of the different treatment methods for this type of pollutant, which began since the mid-nineties of the last century.

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Journal ID : BNIHS-19-05-2022-10335
Title : Interleukin 9 +176 rs1799962 Polymorphism is Associated with Susceptibility to Thyroiditis in Iraqi Patients
Abstract :

The current study aimed to evaluate the association between SNP of IL-9 gene at position +176 and in patients 60 samples with thyroiditis, divided into 30 samples of hyperthyroidism, 5 male and 25 females, their age 23-60 years, and hypothyroidism patients 30 females their age 21-60 years, and controls 31 samples, 3 male and 28 females their age 18-45 years. This study showed a significant increase for both hyper and hypo groups compared with control (42.90±2.11), (41.47±2.11) and (28.0±1.55), under (P<0.05). Study showed, that homozygous CC genotype and C allele is EF for Hashimoto thyroiditis (2.20 and 1.30), with RR (23.6% and 11.9%) respectively, while the heterozygous TC genotype and allele T were considered PF from Hashimoto thyroiditis (0.32 and 0.77) respectively. The current study showed, homozygous TT genotype and T allele were considered EF for Graves' disease (4.20 and 3.56), with RR (50.8% and 52.8%) respectively. While the homozygous CC genotype and C allele recorded a significant decrease in patients CC genotype and C allele were considered PF from Graves’ disease 0.30 and 0.28 respectively. Same result recorded TC genotype (13.33%), also considered PF from Graves' disease 22.58 %. This study suggest that SNP of IL-9 gene at position +176 may have a role in pathogenic mechanisms, and an association (positive and negative) with Graves’ disease and Hashimoto thyroiditis in samples of Iraqi patients.

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