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Title : Clinical significance and role of CEA level in diagnosis of colorectal cancer
Abstract :Colorectal cancer is a widespread illness that begins with unusual growth of the inner colon or rectum and progresses to the entire thickness of the epithelial lining before spreading to nearby lymph nodes and tissues and eventually distant metastases. It’s one of the most challenging cancers to treat, with severe symptoms that worsen, become more obvious and specific as the disease progresses, with a high mortality rate and minimal survival if detected late or untreated. The serum carcinoembryonic antigen isn't created in large amounts after birth, but it's raised in colorectal cancer. The participants of the study were 180 cases, comprising patients and healthy people, separated into two categories: The first had 90 patients, 47 men, and 43 women. The second group had 90 healthy individuals including 60 men and 30 women. All individuals were subjected to blood sampling for measuring their serum CEA using the Sandwich principle (Cobas E411). The mean serum CEA concentration was significantly higher (P = 0.013) in CRC than healthy controls. Determine the effectiveness and validity of blood CEA levels in diagnosing colorectal cancer.
Title : Immuno-inflammatory predictors and pathological features in COVID-19 patients
Abstract :COVID-19 diseases due to the SARS-Cov-2 virus have become a global infectious disease. It is, therefore, crucial to investigate biomarkers that are involved in the pathogenicity and severity of the disease. This study aimed to investigate some immune-inflammatory and pathological biomarkers s during COVID-19 diseases. After providing written consent, 5 ml blood samples were drawn from 121 COVID-19 patients confirmed by Real Time Polymerase Chain Reaction (RT-PCR), including 77 Male and 44 Female COVID-19 cases with 52.64 years of mean age. Clinical analysis was performed including White blood cells (WBC), Lymphocytes (Lymph), D-dimer, Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), Ferritin, creatinine, urea and blood glucose were analysed after adjusting for sex, presence of comorbidity, weight and smoking status. Elevation of some clinical parameters was elevated in severe COVI D-19 patients compared to mild patients, also female COVID-19 patients had higher WBC and ferritin level compared to male patients. It can be concluded that some clinical biomarkers in COVID-19 patients, such as WBC, lymph percent, D-Dimer, Ferritin, ESR, CRP urea, and creatinine, are distinct predictive indicators for severe male COVID-19 patients, which are more frequent than opposite-sex gender.
Title : Water quality assessment of Sawyer river using some environmental indices.
Abstract :The assessment of water quality is very important for knowing its suitability for various purposes. Water quality index (WQI) indicates the quality of water in terms of index number for any intended use. It is defined as a rating reflecting the composite influence of different water quality parameters were taken for calculation of water quality index. The water quality of the Al-Sawyer River, which is the main branch of the Euphrates River in the Al-Muthanna Governorate in southern Iraq, was assessed. These study evaluated the water quality using four models of water indices, which are weighted Arithmetic (WA-WQI), Canadian Council of Environment Ministers for the Water Quality Index (CCME), Heavy Metals Index (HPI). as well as Minimum operator index (min). Monthly water samples were collected from three stations on the river from November 2020 to October 2021 and were analyzed, The results of the study showed used the CCME Index to assess the quality of water for drinking, irrigation and living aquatic purposes. And the results were (41.52,Poor) for drinking, ccme for irrigation water value ranged (60.5-93.91, Fair to Good),as well as for aquatic living ranged (Poor –Fair), The results indicated that the river water quality is unsuitable for drinking, but it is suitable for irrigation and aquatic life. WA-WQI Indicator Results showed (237.5, 184.6, 228.6) in three stations respectively, The results of this indices also revealed that the river water is unfit for human consumption. The results indicated that the values of HPI of the three stations were (238.8, 185.5, 230.2) High Polluted in the all stations. The Results WQImin ranged between (Bad to Good water).
Title : Lymphocytopenia and Epstein-Barr virus (EBV) infection in Cancer patients were treated with chemotherapy in Najaf governorates-Iraq
Abstract :The Epstein-Barr virus (EBV) is responsible for the majority of human malignancies. Chemotherapy patients have low white blood cell (WBC) counts, which increases the risk of infection and is Iraq's top public health issue. WBC can destroy tumors and assist in infection control, but they also increase tumor development, metastasis, and treatment resistance. The body is more susceptible to infection when the lymphocytes count is low. The goal of our research was to show if there was a link between low lymphocyte counts and EBV infection in cancer patients. The study included patients (cross-sectional study). The Middle Euphrates Center for Cancer split the participants into two groups: 90 cancer patients with Lymphocytopenia and 90 (no Lymphocytopenia) 180 blood samples were taken, a blood sample from a cancer patient undergoing chemo (period between February, 2021 and August, 2021). The patients' ages varied from 10 to 70. Subjects' samples were divided into In the CBC test, entire blood samples were tested for EBV Ags, IgM, and IgG, CBC test, amount of lymphocytes is 1000/mcL (1 109/L). Using commercial ELISA kits, patients' blood samples were tested for EBV Ag, IgM, and IgG antibodies. This research examined three Lymphocytopenia symptoms (mild, moderate, and severe). Mild patients made up 35.6%, moderate 30%, and severe 34.4%. The three degrees of Lymphocytopenia were categorized by age groups; with category (51-70) having the most severe cases 43.3%. The 31-50 age groups came in second with 33.3 %. These tests looked for EBV Ag, IgM antibody, and IgG antibody in all three Lymphocytopenia grades. The original data showed 90 people with 29 IgM-positive cases (38%), 43IgG-positive cases 52%, and EBV Ag positive cases 18 it found mild results in 32 cases, including 9 IgM and 11 IgG positives. There were also 7 EBV Ag positive patients. The moderate group included 9 IgM positive, 11 IgG positive, and 7 EBV positive patients. In terms of severity, 10 individuals had IgM, 18 had IgG, and 3 had Ags. According to the results of the current investigation, cancer patients with Lymphocytopenia were more likely to have viral infections than cancer patients without Lymphocytopenia.
Title : Cohort Study D3 Injection Dose 100000 IU Transdermal They Have Suffered with Warts
Abstract :Skin warts is the most common viral skin infection, Effective vitamin D3 has been utilized to treat skin warts nowadays, in the past many other methods were used to treat warts like electrocautery, cryotherapy, or laser ablation. Intralesional substance D3 infusion is now used in the management of all type of this disease. Forty-five patients were treated with vitamin D3 injection (males and females), all got an intralesional infusion of 0.2 mL of nutrient of this 100,000 IU into the foundation of mother affected lesion for two meetings and first month and fourth months after the methodology. The level of the reaction was characterized as complete, fractional, and no response. To assess the viability and security of intralesional (IL) nutrient D3 100,000 IU was infused in the treatment of skin warts. A total of 45 patients who complain of skin warts and accept to participate in this study who attended the dermatology department of both genders were included in this study, aged between 20-45 years old randomly selected. This study showed that the efficacy of vitamin D3 in the treatment of skin warts was 86.6 %. The new treatment of skin warts using vitamin D3 100,000 IU injection is more effective than the traditional warts treatment.
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