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Bulletin of National Institute of Health Sciences

Journal ID : BNIHS-12-04-2022-10262
Title : Nurse's Knowledge about managing COVID-19 Patients at Intensive Care Unit in Mosul Teaching Hospitals
Abstract :

The workers in the field of health, especially nurses, are considered the first line of prevention (the White Army) in facing health challenges because of their direct contact with the disease and the patient. They play a fundamental role in preventing the spread of COVID 19 by providing appropriate care and required preventive measures. The study to assess nurse's knowledge about COVID-19 patients in the intensive care. To achieve the aims of the current investigation, a cross-sectional descriptive study design was used, with knowledge questions provided to 40 participants to complete beginning on (15 April 2020 to 20 August 2020). To achieve the ultimate aim and make use of the instrument of the electronic research questionnaire tailored to the purpose of collecting data for the research study connected to COVID-19, it is consist of two sections: Section one: Self-Administered Survey Sheet Regarding Descriptive Characteristics of the Nurse Working (age, gender, years of experience, location of employment, and level of education). Section two: the knowledge survey comprised (35) items about COVID-19. A total of (40) nurses were enrolled in this study, with a mean age of (34.17 ± 8.77) years, most of them were male (85 %), the majority of them had less than five years' experience (67.5%), the highest percentage of nurses (70%) working in the morning shift. The majority of them had a university education level (75%)—the most significant number of nurses working in Ibn Sina Hospital. Most nurses do not have a course of knowledge about the COVID 19 virus by 70%. They showed adequate knowledge about COVID 19. The significant majority of nurses have a sufficient understanding of COVID-19. The ministry of health authorities should put education interventions and campaigns required for healthcare workers in the hospitals and health centres to know and protect from COVID 19.

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Journal ID : BNIHS-12-04-2022-10261
Title : Mid- Luteal estradiol level as predictor marker of successful pregnancy in women undergo ovulation induction in Baquba city
Abstract :

The aim of the current study was to determine the levels E2, Prolactin, TSH, LH and FSH in mid luteal phase and depended it as a good marker to early predict for pregnancy in women. A total of 58 healthy women aged 20–40 years which undergo ovulation induction included in this study from Al- Batool Teaching Hospital and private clinic in Diyala province, Iraq, during February 2021 to February 2022. Ultrasound scanning by transvaginal to all women of this study were recorded to assess ovarian efficiency, moreover blood samples got in day 12 of the cycle to determine levels of E2, Prolactin, TSH, LH and FSH. The result of this study showed significant difference increasing (p ≤ 0.05) serum estrogen concentration in pregnant female differentiated with non- conceived and without any significant difference for others hormones. The study recorded significant positive relationship between type of infertility with Period of infertility in nonpregnant women at the 0.05 level. Also, there is a significant positive relationship in non-pregnant women among age with Period of infertility and Period of treatment at the 0.05 level, and at the 0.01 level with the type of infertility that when the age increases the Period of infertility and Period of treatment and vice versa. Inconclusion the study showed E2 hormone as a significant predict marker for pregnancy in women during mid luteal phase.

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Journal ID : BNIHS-12-04-2022-10260
Title : AECA and ANA in threatened abortion women in Babylon province
Abstract :

Threatened abortion is a common pregnancy complication that affects approximately 20% of all pregnancies. The aim of this study is to assess the presence of autoantibodies (anti-endothelial cell antibodies and antinuclear antibodies) in the study groups and their significance in the diagnosis of threatened abortion. The study was carried out in the Iraqi city of Babylon. This study included 90 subjects who were separated into three groups: 30 threatened abortion patients, 30 healthy pregnant women, and 30 healthy non pregnant women. All of the study groups were between the ages of 20 and 35 years old. Assessment of autoantibodies (AECA and ANA) in the studied groups blood samples from all subjects were taken. It was made using the Enzyme linked Immunosorbent Assay (ELISA) technology. AECA positive frequency in TA group was (13.3 %) with a significant difference (p= 0.015). While the ANA positive frequency in TA group was (10.0 %) with a significant difference (p= 0.045). In conclusion, immunological tests (AECA and ANA) play an important role in prognosis and/or diagnosis of threatened abortion.

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Journal ID : BNIHS-12-04-2022-10259
Title : Detection of preptin and insulin like growth factor 2 receptor in the sera of type 2 diabetic patients in Kirkuk city
Abstract :

Type 2 diabetes is a multifactorial disease and due to a combination of genetic and environmental risk factors. The paper aims to investigate serum preptin, and insulin like growth factor 2 receptor and their role in T2DM patients in a Kirkuk population. The hospital-based cases- control study was conducted for patients with Type 2 diabetes patients that attended of the Diabetic center in K1 Hospital and Consultation Clinic of Kirkuk, and Azadi Teaching Hospital in Kirkuk during the period from March 2021– August 2021 A total of 150 subjects were screened for concentration of preptin, and insulin like growth factor 2 receptor (IGF2R), glucose, and whole blood was estimated for glycated hemoglobin (HbA1C) especially in relation to (age, and gender) from all patients were recorded. Among the Type 2 diabetes patients recruited for this study, serum glucose fasting blood sugar concentration which showed that T2DM patients had average 168.16± 32.69 mg/dl was significantly higher than in control subjects, p < .001, and for HbA1C the average of T2DM patients whose had 9.87± 2.08 % was also significantly different from control group, p < 0.001. preptin levels that the majority of patients with T2DM had the mean of (66.79± 46.67 pg/ml) that was significantly higher than the mean for control group (17.27± 4.05 pg/ml).U = 4759, p < .001. According to IGF_2R levels revealed that the mean for T2DM patients (23.20± 10.95μg/ml) was significantly higher than the mean for control group (5.98± 3.90 μg/ml), U = 4747.5, p < .001. Greater preptin concentrations in recently identified in T2DM subjects recommended that preptin may performance a role in Type 2 Diabetes Millets causation. Soluble IGF2R could directly affect susceptibility to type 2diabetes that influence insulin resistance.

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Journal ID : BNIHS-12-04-2022-10258
Title : Significance of renal Allograft Biopsy in correlation with its survival, clinic-biochemical panels
Abstract :

Renal transplantation is the treatment of choice for most patients with end stage renal disease., renal biopsy is the gold standard to assess the causes of renal allograft dysfunction. This study was designed to evaluate and designate renal lesions according to Banff schema and to determine the safety and efficacy of the practice of renal allograft biopsy and verify its impact on the management of kidney transplant patients presenting with graft dysfunction and its correlation with graft survival and clinic-biochemical parameters. In this cross-sectional study, all renal allograft biopsies obtained from renal transplant patients at Baghdad teaching hospital in Iraq during 2013-2014 were studied. Evaluations were made according to the Banff classification 2009. Clinical and biochemical data and pathological reports were collected and analyzed using SPSS analysis method. We studied 55 renal allograft biopsies of 55 adult patients (61.8% males, 38.2%females) mean age was 32.4 years, performed in the medical city complex from February 2013 to May 2014. All the biopsies were performed with a guidance of ultrasound. The procedure, complications, histological diagnoses and impact of the biopsy data on patients' management were recorded. Thirty percent of the biopsies were performed in the first 12 months post-transplantation and 70 % were performed after the 60th month. Adequate biopsy was achieved in 90.9% of the patients. Acute rejection was diagnosed in 36.4% of the biopsies and chronic allograft Nephropathy in 41%, and they were the most common histological patterns in the study. The commonest causes of graft dysfunction after kidney transplant were IF/TA. Living donors were found to be important sources for kidney transplantation in Iraq. Allograft biopsy was a useful and a relatively safe tool for the diagnosis of acute and chronic graft dysfunction in our experience, since there were no major complications and minor complications were rare and with negligible consequences. This procedure using 16-gauge needles also is efficient, as the majority of samples were adequate for diagnostic purposes. None specified symptoms allow for clear differentiation between stable transplants with normal histology and stable transplants with subclinical rejection. Therefore, the protocol allograft biopsy currently remains the preferred tool to screen for subclinical transplant injury. A protocol biopsy is an excellent method for the early diagnosis of disorders in the transplanted kidney and to monitor the effects of immunosuppression. The protocol biopsy, followed by appropriate treatment, promotes preservation of kidney allograft function and therefore improves long-term graft survival.

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